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New lung cancer combo shown to extend survival by eight months

A new drug combination extended survival by more than eight months in patients with extensive-stage small cell lung cancer, according to a late-stage clinical trial.
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The US pharmaceutical company Amgen has evaluated its T-cell engager Imdelltra (tarlatamab) in combination with AstraZeneca’s Imfinzi (durvalumab), reporting strikingly positive results in a phase III trial.

The treatment was given as first-line maintenance therapy to patients with extensive-stage small cell lung cancer (SCLC) whose disease had not progressed following initial treatment with Imfinzi and chemotherapy.

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